Medicial Paper:

Fuyuan decoction prevents nasopharyngeal carcinoma metastasis by inhibiting circulating tumor cells/ endothelial cells interplay and enhancing anti-cancer immune response

The FYD consists of nine different herbs: Actindia arguta (Siebold & Zucc.) Planch. ex Miq. [Actinidiaceae; Actindia arguta root] 25 g, S. barbata D.Don [Lamiaceae; Scutellaria barbata whole plant] 20 g, Scleromitrion diffusum (Willd.) R.J.Wang [Rubiaceae; Scleromitrion diffusum whole plant] 40 g, Iphigenia indica (L.) A.Gray ex Kunth [Colchicaceae; Iphigenia indica pseudobulb] 4 g, Salvia miltiorrhiza Bunge [Lamiaceae; Salviae miltiorrhizae radix et rhizome] 20 g, G. lucidum (Curtis) P. Karst. 15 g, Panax ginseng C.A.Mey. [Araliaceae; Panax ginseng radix et rhizome] 12 g, Lycium chinense Mill. [Solanaceae; Lycium chinense fruit] 12 g, and Astragalus mongholicus Bunge [Fabaceae; Astragalus mongholicus root] 20 g. All herbs were purchased from Jiangxi Kangqingtang Herbal decoction Pieces Co., Ltd. (Zhangshu, China). FYD standard decoction was prepared according to “Management standard of traditional Chinese medicine (TCM) decoction in medical institutions” (Wang et al., 2019). The water-mixed raw materials were soak for 30 min, then decocted for another 45 min and filtered for collection of the filtrate. The residue was decocted again and filtered twice. The filtrates were then freeze-dried to obtain FYD powder.

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